Pesquisa | BVS Violência e Saúde

1.

Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways.

Bellono, Nicholas W; Bayrer, James R; Leitch, Duncan B; Castro, Joel; Zhang, Chuchu; O'Donnell, Tracey A; Brierley, Stuart M; Ingraham, Holly A; Julius, David.

Cell ; 170(1): 185-198.e16, 2017 Jun 29.

Artigo em Inglês | MEDLINE | ID: mdl-28648659

2.

Gut enterochromaffin cells drive visceral pain and anxiety.

Bayrer, James R; Castro, Joel; Venkataraman, Archana; Touhara, Kouki K; Rossen, Nathan D; Morrie, Ryan D; Maddern, Jessica; Hendry, Aenea; Braverman, Kristina N; Garcia-Caraballo, Sonia; Schober, Gudrun; Brizuela, Mariana; Castro Navarro, Fernanda M; Bueno-Silva, Carla; Ingraham, Holly A; Brierley, Stuart M; Julius, David.

Nature ; 616(7955): 137-142, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36949192

3.

Trefoil Factor Family: Unresolved Questions and Clinical Perspectives.

Braga Emidio, Nayara; Hoffmann, Werner; Brierley, Stuart M; Muttenthaler, Markus.

Trends Biochem Sci ; 44(5): 387-390, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30792027

4.

Peripheral and central neuroplasticity in a mouse model of endometriosis.

Castro, Joel; Maddern, Jessica; Erickson, Andelain; Harrington, Andrea M; Brierley, Stuart M.

J Neurochem ; 2023 May 11.

Artigo em Inglês | MEDLINE | ID: mdl-37165846

5.

The voltage-gated sodium channel Na_V 1.7 underlies endometriosis-associated chronic pelvic pain.

Castro, Joel; Maddern, Jessica; Chow, Chun Yuen; Tran, Poanna; Vetter, Irina; King, Glenn F; Brierley, Stuart M.

J Neurochem ; 2023 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-36840383

6.

Visceral Pain.

Grundy, Luke; Erickson, Andelain; Brierley, Stuart M.

Annu Rev Physiol ; 81: 261-284, 2019 02 10.

Artigo em Inglês | MEDLINE | ID: mdl-30379615

7.

Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension.

Grundy, Luke; Caldwell, Ashlee; Garcia-Caraballo, Sonia; Grundy, David; Spencer, Nick J; Dong, Xinzhong; Castro, Joel; Harrington, Andrea M; Brierley, Stuart M.

J Neurosci ; 41(17): 3900-3916, 2021 04 28.

Artigo em Inglês | MEDLINE | ID: mdl-33727332

8.

Orai1- and Orai2-, but not Orai3-mediated I_CRAC is regulated by intracellular pH.

Rychkov, Grigori Y; Zhou, Fiona H; Adams, Melissa K; Brierley, Stuart M; Ma, Linlin; Barritt, Greg J.

J Physiol ; 600(3): 623-643, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34877682

9.

A mouse model of endometriosis that displays vaginal, colon, cutaneous, and bladder sensory comorbidities.

Castro, Joel; Maddern, Jessica; Grundy, Luke; Manavis, Jim; Harrington, Andrea M; Schober, Gudrun; Brierley, Stuart M.

FASEB J ; 35(4): e21430, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33749885

10.

Food for thought about the immune drivers of gut pain.

Brierley, Stuart M.

Nature ; 590(7844): 41-43, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33441989

11.

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.

Osteen, Jeremiah D; Herzig, Volker; Gilchrist, John; Emrick, Joshua J; Zhang, Chuchu; Wang, Xidao; Castro, Joel; Garcia-Caraballo, Sonia; Grundy, Luke; Rychkov, Grigori Y; Weyer, Andy D; Dekan, Zoltan; Undheim, Eivind A B; Alewood, Paul; Stucky, Cheryl L; Brierley, Stuart M; Basbaum, Allan I; Bosmans, Frank; King, Glenn F; Julius, David.

Nature ; 534(7608): 494-9, 2016 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-27281198

12.

Pruritogenic mechanisms and gut sensation: putting the "irritant" into irritable bowel syndrome.

Brizuela, Mariana; Castro, Joel; Harrington, Andrea M; Brierley, Stuart M.

Am J Physiol Gastrointest Liver Physiol ; 320(6): G1131-G1141, 2021 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-33949199

13.

Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.

Jimenez-Vargas, Nestor N; Pattison, Luke A; Zhao, Peishen; Lieu, TinaMarie; Latorre, Rocco; Jensen, Dane D; Castro, Joel; Aurelio, Luigi; Le, Giang T; Flynn, Bernard; Herenbrink, Carmen Klein; Yeatman, Holly R; Edgington-Mitchell, Laura; Porter, Christopher J H; Halls, Michelle L; Canals, Meritxell; Veldhuis, Nicholas A; Poole, Daniel P; McLean, Peter; Hicks, Gareth A; Scheff, Nicole; Chen, Elyssa; Bhattacharya, Aditi; Schmidt, Brian L; Brierley, Stuart M; Vanner, Stephen J; Bunnett, Nigel W.

Proc Natl Acad Sci U S A ; 115(31): E7438-E7447, 2018 07 31.

Artigo em Inglês | MEDLINE | ID: mdl-30012612

14.

Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H₁ receptor and TRPV1.

Grundy, Luke; Caldwell, Ashlee; Garcia Caraballo, Sonia; Erickson, Andelain; Schober, Gudrun; Castro, Joel; Harrington, Andrea M; Brierley, Stuart M.

Am J Physiol Renal Physiol ; 318(2): F298-F314, 2020 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-31790304

15.

Na_V 1.6 regulates excitability of mechanosensitive sensory neurons.

Israel, Mathilde R; Tanaka, Brian S; Castro, Joel; Thongyoo, Panumart; Robinson, Samuel D; Zhao, Peng; Deuis, Jennifer R; Craik, David J; Durek, Thomas; Brierley, Stuart M; Waxman, Stephen G; Dib-Hajj, Sulayman D; Vetter, Irina.

J Physiol ; 597(14): 3751-3768, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31087362

16.

Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord.

Harrington, Andrea M; Caraballo, Sonia Garcia; Maddern, Jessica E; Grundy, Luke; Castro, Joel; Brierley, Stuart M.

Am J Physiol Gastrointest Liver Physiol ; 317(3): G285-G303, 2019 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-31188624

17.

G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease.

Lee, Ming-Chin; McCubbin, James A; Christensen, Anne D; Poole, Daniel P; Rajasekhar, Pradeep; Lieu, TinaMarie; Bunnett, Nigel W; Garcia-Caraballo, Sonia; Erickson, Andelain; Brierley, Stuart M; Saleh, Reem; Achuthan, Adrian; Fleetwood, Andrew J; Anderson, Robin L; Hamilton, John A; Cook, Andrew D.

J Immunol ; 198(9): 3565-3575, 2017 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-28320832

18.

Voltage-gated sodium channels: (Na_V )igating the field to determine their contribution to visceral nociception.

Erickson, Andelain; Deiteren, Annemie; Harrington, Andrea M; Garcia-Caraballo, Sonia; Castro, Joel; Caldwell, Ashlee; Grundy, Luke; Brierley, Stuart M.

J Physiol ; 596(5): 785-807, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29318638

19.

NKA enhances bladder-afferent mechanosensitivity via urothelial and detrusor activation.

Grundy, Luke; Chess-Williams, Russ; Brierley, Stuart M; Mills, Kylie; Moore, Kate H; Mansfield, Kylie; Rose'Meyer, Roselyn; Sellers, Donna; Grundy, David.

Am J Physiol Renal Physiol ; 315(4): F1174-F1185, 2018 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-29897284

20.

Cross-organ sensitization between the colon and bladder: to pee or not to pee?

Grundy, Luke; Brierley, Stuart M.

Am J Physiol Gastrointest Liver Physiol ; 314(3): G301-G308, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29146678

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